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Beans vs. belly fat: could a cup a day cut cancer risk?

NCT ID NCT02843425

Prevention Sponsor: M.D. Anderson Cancer Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding canned navy beans to your daily diet can improve gut bacteria and lower obesity-related cancer risk. About 71 adults who are overweight and have a history of colorectal polyps or cancer will eat beans for 8 weeks. Researchers will check changes in stool and blood markers to see if beans help protect against colorectal cancer.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
canned navy beans
What this could lead to
If it works, this could point toward a simple dietary change to help prevent colorectal cancer in people with a history of polyps or cancer.
What could go wrong
This is a small, early-stage study with only 71 participants, so results may not apply to everyone. Eating beans may cause digestive discomfort for some people.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

71 people

The number who actually took part.

Started

Jul 2016

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adult men and women 30+ years of age 2. Meet criteria for overweight or obesity via BMI or waist size 3. Underwent colonoscopy screening within the past 10 years 4. History of pathology-confirmed precancerous polyp of the colon or rectum; OR Colorectal cancer survivor who has completed treatment with adequate maintenance of bowel length (eligible: hemicolectomy or low anterior resection; ineligible: total or near total colectomy, greater than 10 cm of small bowel resection) and normalized bowel habits 5. English-speaking and reside in the greater Houston/outlying areas and/or willing to travel for study-related visits at MD Anderson 6. Ability to complete web-based dietary assessments twice per week 7. Willingness to provide stool samples and undergo venipuncture 8. Willingness to consume/avoid beans as instructed during the 16 weeks from randomization Exclusion Criteria: 1. Antibiotic use in the past month and unable/unwilling to be deferred to a later recruitment date 2. Current smoker 3. Heavy drinker (defined as more than 14 drinks per week) 4. Currently taking exclusionary prescription medications (including cytokines, immunosuppressive agents, chemopreventive drugs, bile acid sequestrants/selective cholesterol absorption inhibitors) 5. Regularly taking anti flatulence medications, probiotics and/or fiber supplements and unable/unwilling to discontinue for the purpose of the study 6. Major dietary restrictions relevant to the intervention 7. Hereditary colorectal cancer syndromes 8. Pregnant or lactating or planning to become pregnant

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Conditions

The condition(s) this trial relates to.

colorectal adenoma colorectal cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colorectal cancer prevention

Contacts and locations

Locations

  • University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.