Blood test may reveal hidden heart damage in AFib patients
NCT ID NCT07648329
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at 150 people with persistent atrial fibrillation (a type of irregular heartbeat) who are scheduled for a heart procedure called ablation. Researchers want to see if levels of a protein called BDNF in the blood are linked to signs of heart muscle damage (atrial cardiomyopathy). By comparing blood samples with heart mapping data taken during the ablation, they hope to better understand the connection between BDNF and heart health, and whether BDNF levels can predict future heart rhythm problems.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 150 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jul 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients scheduled to undergo their first ablation procedure for persistent atrial fibrillation at the Dijon Bourgogne University Hospital.
- Ages
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18 years and older
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Participants who have provided written consent * Patients aged 18 years or older. * Patients scheduled to undergo their first ablation procedure for persistent atrial fibrillation at the Dijon Bourgogne University Hospital Exclusion Criteria: * A person who is not enrolled in or eligible for a social security program * A person subject to a legal protective measure (guardianship, conservatorship) * Person subject to a judicial safeguard measure * Pregnant or breastfeeding woman * Adult who is legally incapacitated or unable to give consent * Ablation of paroxysmal AF with or without electroanatomical mapping
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Chu Dijon Bourogne
Dijon, 21000, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Two ways to quiet a racing heart: trial pits hybrid ablation against standard catheter treatment
- Can a breathing workout and walks help dialysis patients with irregular heartbeats?
- Why do some children arrive at the ER with a racing or skipping heart?
- Zapping the ear: a new way to stop Post-Surgery heart rhythm problems?
- Can a new mapping and ablation system fix recurring atrial fibrillation?