Can a simple exercise program reverse muscle loss in seniors?
NCT ID NCT07601321
First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 2 times
Summary
This study tests a 12-week resistance exercise program designed to help older adults with sarcopenia (age-related muscle loss). The program uses behavior change techniques like education, rewards, and reminders to keep participants on track. One hundred community-dwelling adults will be randomly assigned to start the program right away or wait 3 months. The goal is to see if the program improves muscle mass, strength, and physical performance.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Behavior Change Wheel (BCW)-based resistance exercise program
- What this could lead to
- If successful, this program could offer an effective, non-drug way to improve muscle strength and physical function in older adults with sarcopenia.
- What could go wrong
- This is a small, early-stage trial with only 100 participants, and results may not apply to all people with sarcopenia. The program requires regular attendance and may not work for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Meet the diagnostic criteria for sarcopenia according to the Asian Working Group for Sarcopenia (AWGS) 2025: Low muscle mass (SMI measured by BIA): For age ≥ 65, Male \< 7.0 kg/m², Female \< 5.7 kg/m²; For age 50-64, Male \< 7.6 kg/m², Female \< 5.7 kg/m². Low muscle strength (Handgrip strength): For age ≥ 65, Male \< 28 kg, Female \< 18 kg; For age 50-64, Male \< 34 kg, Female \< 20 kg. Ability to walk independently without assistive devices. Clear consciousness and stable medical condition. Willingness to participate, commit to the exercise protocol, and provide signed informed consent. Proficiency in using a smartphone. Exclusion Criteria: * Presence of metal implants, such as cardiac pacemakers, stents, steel plates, or artificial joints (due to BIA measurement constraints). Cognitive impairment, epilepsy, other neurological disorders, or severe mental illness that prevents cooperation with the study. Inability to complete the exercise intervention due to severe cardiovascular or musculoskeletal diseases. Severe organ dysfunction (e.g., heart failure), organ failure, or active infection. Inability to maintain adherence or significant missing data (participants who withdraw or are lost to follow-up).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Tianshui Wulin Sub-district Community Health Service Center
Hangzhou, Zhejiang, China
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