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Mind-Controlled hand therapy shows promise for spinal cord injury recovery

NCT ID NCT05637775

Disease control Sponsor: I.R.C.C.S. Fondazione Santa Lucia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether a brain-computer interface (BCI) training program could improve hand and arm function in people with recent spinal cord injuries. Thirty participants used a system that reads brain signals during hand motor imagery exercises. The goal was to see if this approach could boost brain plasticity and recovery better than standard motor imagery alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Brain-computer interface (BCI) training with motor imagery
What this could lead to
If successful, this approach could offer a new rehabilitation tool to improve hand and arm function after spinal cord injury.
What could go wrong
This is a small, early-stage study (30 participants) with no blinding, so results may not apply widely. The intervention is complex and requires specialized equipment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Nov 2022

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * subacute cervical SCI (30-90 days from event) * classification according to ISNCSCI AIS A-D, lesion level C1-T1 * Upper Extremity Motor Score (UEMS) \< 40 Exclusion Criteria: * other conditions (present or previous) potentially affecting sensorimotor upper limb function * inability to give informed consent and understand the requirements for the training

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Conditions

The condition(s) this trial relates to.

Motor Disorders movement disorder spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Motor disorders Spinal cord injuries

Contacts and locations

Locations

  • Neurorehabilitation Units- Fondazione Santa Lucia, IRCCS

    Rome, Italy, 00179, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.