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TB prevention vaccine trial cut short: only 16 of 2,000 enrolled

NCT ID NCT04453293

First seen Jan 05, 2026 · Last updated May 20, 2026 · Updated 20 times

Summary

This study aimed to see if a single dose of the BCG vaccine, given before travel, could prevent tuberculosis (TB) infection in healthy adults visiting countries with high TB rates. Researchers planned to enroll 2,000 participants, but the trial was terminated early with only 16 enrolled. The main goal was to compare TB infection rates between those who got the vaccine and those who got a placebo.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Hope Clinic of the Emory University Vaccine Center, Emory University

    Decatur, Georgia, 30030, United States

  • Johns Hopkins Bloomberg School of Public Health, Department of International Health, Center for Immunization Research

    Baltimore, Maryland, 21205, United States

  • MedStar Washington Hospital Center/MedStar Health Research Institute

    Washington D.C., District of Columbia, 20010, United States

  • The Brigham and Women's Hospital Center for Clinical Investigation

    Boston, Massachusetts, 02115, United States

  • University of Utah School of Medicine

    Salt Lake City, Utah, 84108, United States

  • Yale University School of Medicine

    New Haven, Connecticut, 06510, United States

Conditions

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