Can amino acid shakes help liver patients regain muscle?
NCT ID NCT06121479
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 37 times
Summary
This study tests whether taking branched-chain amino acid (BCAA) supplements twice daily for 12 weeks can improve muscle thickness and nutrition in people with decompensated cirrhosis and ascites (fluid in the belly). Thirty adults with low albumin levels will receive the supplement and undergo measurements of muscle, strength, and blood markers. The goal is to see if BCAA can counteract muscle wasting common in advanced liver disease.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Division of Gastroenterology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
Bangkok, Bangkok, 10700, Thailand
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
branched-chain amino acids (BCAA)
What this could lead to
If successful, this could show that BCAA supplements help improve muscle mass and nutrition in people with advanced liver disease and fluid buildup.
What could go wrong
This is a small pilot study with only 30 participants, so results may not apply to everyone. It focuses on short-term nutritional changes, not long-term survival or liver function.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.