Can amino acid shakes help liver patients regain muscle?

NCT ID NCT06121479

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether taking branched-chain amino acid (BCAA) supplements twice daily for 12 weeks can improve muscle thickness and nutrition in people with decompensated cirrhosis and ascites (fluid in the belly). Thirty adults with low albumin levels will receive the supplement and undergo measurements of muscle, strength, and blood markers. The goal is to see if BCAA can counteract muscle wasting common in advanced liver disease.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
branched-chain amino acids (BCAA)
What this could lead to
If successful, this could show that BCAA supplements help improve muscle mass and nutrition in people with advanced liver disease and fluid buildup.
What could go wrong
This is a small pilot study with only 30 participants, so results may not apply to everyone. It focuses on short-term nutritional changes, not long-term survival or liver function.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Division of Gastroenterology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

    Bangkok, Bangkok, 10700, Thailand

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