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Blood test may end need for live wasp stings to check allergy treatment

NCT ID NCT04438525

Diagnosis Sponsor: Medical University of Graz Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a blood test called BAT inhibition can replace live insect sting challenges for people with wasp venom allergy. Currently, sting challenges are the only reliable way to see if venom immunotherapy is working, but they are not widely available. Researchers will compare the blood test results with sting challenge outcomes in 219 adults to see if the blood test can accurately measure protection.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
blood test (BAT inhibition)
What this could lead to
If successful, this blood test could replace live sting challenges, making it easier and safer to check if venom immunotherapy is protecting patients from allergic reactions.
What could go wrong
This is a diagnostic study, not a treatment trial. The test may not prove reliable enough to replace sting challenges, and results need confirmation in a larger group.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 219 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2021

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Legally competent male and female subjects who are currently treated or who have been treated with vespid venom immunotherapy * Age ≥18 and ≤70 years * Written consent of the participant after being informed Exclusion Criteria: * Pregnancy * Autoimmune disease * Uncontrolled cardiovascular disease * Uncontrolled asthma

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Conditions

The condition(s) this trial relates to.

venom allergy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Vespid venom allergy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Department of Dermatology and Venerology, Medical University of Graz

    RECRUITING

    Graz, 8036, Austria