Simple brush test could revolutionize cancer surveillance for Barrett's patients
NCT ID NCT06523374
First seen Feb 28, 2026 · Last updated Jun 21, 2026 · Updated 15 times
Summary
This pilot study is testing a new method using a brush to collect cells from the esophagus during a routine endoscopy. The goal is to see if these samples can help predict which patients with Barrett's esophagus are at higher risk of developing esophageal cancer. Researchers will also analyze the samples using advanced genetic techniques and ask patients about their quality of life and cancer worries. The study involves 50 participants and aims to lay the groundwork for a larger trial that could lead to more personalized and cost-effective cancer surveillance.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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AZ Delta
RECRUITINGRoeselare, 8800, Belgium
Contact Phone: •••-•••-••••
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CHU LILLE - Centre Hospitalier Universitaire de Lille
RECRUITINGLille, 59000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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IRCCS Ospedale San Raffaele
RECRUITINGMilan, Milano, 20132, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Karolinska University Hospital
RECRUITINGSolna, SE-171 76, Sweden
Contact Email: •••••@•••••
Contact
Contact
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Rigshospitalet
RECRUITINGCopenhagen, 2100, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sint-Augustinus Hospital (ZAS)
RECRUITINGWilrijk, Antwerpen, 2610, Belgium
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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St James's Hospital
RECRUITINGDublin, D08 NHY1, Ireland
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UZ Gent
RECRUITINGGhent, 9000, Belgium
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University Hospital Antwerp
RECRUITINGEdegem, Antwerpen, 2650, Belgium
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
endoscopic brush cytology
What this could lead to
If successful, this could lead to a simple, cost-effective way to identify which Barrett's esophagus patients are at high risk of cancer, allowing for personalized surveillance and reducing unnecessary procedures.
What could go wrong
This is a small pilot study with only 50 participants, focused on testing methods rather than proving clinical benefit. The approach may not be accurate enough or may not work in larger, more diverse populations.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.