Can a common RA drug also protect your heart and blood?
NCT ID NCT07357649
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether baricitinib, a drug for rheumatoid arthritis, can improve blood clotting and cholesterol levels compared to standard treatments. About 100 adults with active RA will take baricitinib for 3 months. Researchers will measure changes in clotting markers and heart health indicators.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged ≥ 18 years. * Diagnosis of rheumatoid arthritis according to the ACR/EULAR 2010 criteria. * Patients with active rheumatoid arthritis despite conventional treatment. * Ability to provide written informed consent. Exclusion Criteria: * Presence of other autoimmune diseases. * Diabetes mellitus. * Dyslipidemia or use of lipid-lowering therapy within the last 6 months. * Chronic kidney disease. * Chronic liver disease. * Chronic respiratory disease. * History of malignancy. * Pregnancy or breastfeeding. * Alcohol or drug abuse. * Acute or chronic infection. * Current prednisone dose \> 7.5 mg/day. * History of arterial or venous thrombosis. * Use of anticoagulant or antithrombotic drugs within the last 3 months.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Tanta University Hospitals
Tanta, Egypt
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Other studies related to the condition(s) this trial covers.
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- Can a new injection calm rheumatoid arthritis? an early trial puts ZB002 to the test