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Barbell training may be the new Heart-Health hack

NCT ID NCT07578285

Knowledge-focused Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused This study
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 15, 2026 · Updated 2 times

Summary

This study from Mayo Clinic is testing whether a 12-week progressive barbell strength training program can lower blood pressure and improve cholesterol in 200 sedentary adults. Participants will train three times a week with certified coaches. The goal is to see if this type of exercise can improve key markers of heart and metabolic health.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Progressive barbell strength training (squat, deadlift, bench press, overhead press, power clean)
What this could lead to
If successful, this could show that simple barbell training is an effective way to lower blood pressure and improve cholesterol without medication.
What could go wrong
This is an early-stage study with no control group, so results may not prove cause and effect. The benefits might be small or not last beyond the 12-week program.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2027

An estimate. Start dates often move.

Expected to finish

Jan 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

15 to 100 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18-100 years * Sedentary or minimally active (less than 150 minutes of moderate-intensity physical activity per week) * No participation in structured resistance training programs within the past 6 months. * Able to safely participate in resistance training as determined by medical screening * Willing to commit to 3 training sessions per week for 12 weeks * Able to provide informed consent * Willing to obtain pre- and post-intervention laboratory tests from the same laboratory company. Exclusion Criteria: * Current participation in structured resistance training programs * Cardiovascular disease requiring activity restriction * Uncontrolled hypertension (systolic BP \>180 mm Hg or diastolic BP \>110 mm Hg) * Musculoskeletal conditions precluding safe barbell training * Changes in lipid-lowering or antihypertensive medications within 3 months prior to enrollment * Known cardiovascular, metabolic, or renal disease that would preclude safe participation in resistance training

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Conditions

The condition(s) this trial relates to.

hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Blood pressure Fasting glucose Lipid profile

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Mayo Clinic in Arizona

    Scottsdale, Arizona, 85259, United States

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