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Multivitamin may shield ozempic users from hidden nutrient shortages
NCT ID NCT06981936
First seen Jun 25, 2026 · Last updated Sep 03, 2026 · Updated 3 times
Summary
This study tests whether a daily multivitamin tablet can prevent vitamin and mineral deficiencies in people using GLP-1 drugs (like Ozempic or Saxenda) for weight loss. These drugs suppress appetite, which can lead to low nutrient intake. The trial will compare a multivitamin to a placebo over 12 months in 150 adults with obesity. Researchers will measure blood nutrient levels to see if the supplement helps maintain healthy levels.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Balance Tablet (multivitamin and mineral supplement)
- What this could lead to
- If it works, this could show that taking a daily multivitamin helps prevent nutrient deficiencies in people using GLP-1 drugs for weight loss.
- What could go wrong
- This is a relatively small, early-phase trial. The supplement may not prevent all deficiencies, and results may not apply to everyone. There is little risk from the supplement itself.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
-
150 people
The number who actually took part.
- Started
-
May 2025
- Finished
-
May 2026
- Lead sponsor
-
A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * • Adults aged 18-65 years. * BMI ≥ 30 kg/m² (obesity), or BMI ≥ 27 kg/m² with at least one obesity-related comorbidity (e.g., type 2 diabetes, hypertension). * Currently using a GLP-1 receptor agonist medication for weight management (e.g., semaglutide or liraglutide) and planning to continue it for the next year as part of their weight loss regimen. Exclusion Criteria: * • Any pre-existing condition that affects nutrient absorption or metabolism (e.g., malabsorptive gastrointestinal disorders such as celiac disease or inflammatory bowel disease, prior bariatric surgery). * Use of other weight loss medications (besides the GLP-1 RA) or use of high-dose vitamin/mineral supplements or other nutritional supplements that could influence vitamin/mineral status. * Pregnancy or lactation (women of childbearing potential will undergo a pregnancy test and must agree to use contraception during the study). * Known hypersensitivity or allergy to components of the Balance multivitamin formulation. * Significant chronic illnesses (e.g., end-stage renal disease, advanced liver disease) that in the investigator's judgment would interfere with participation or outcomes of the study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Facility Name: The surgical department of Medical Research Institute Hospital, Alexandria University, Alexandria, Facility
Alexandria, Egypt
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