Botox for stiff leg: could it increase falls? new study investigates
NCT ID NCT07108920
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 26 times
Summary
This study looks at whether Botox injections in the thigh muscle (rectus femoris) affect balance and fall risk in people with a stiff knee gait caused by stroke, brain injury, or multiple sclerosis. Researchers will measure balance and walking before and after the injection using standard tests like the Timed Up and Go and Berg Balance Scale. The goal is to see if the muscle-relaxing effect of Botox might unintentionally increase the chance of falling.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Centre de Médecine Physique et de Réadaptation Bretegnier
RECRUITINGHéricourt, Nord Franche-Comté, 70 400, France
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Botulinum toxin (Botox)
What this could lead to
If this study finds that Botox does not increase fall risk, it could reassure patients and doctors that the current treatment is safe for balance.
What could go wrong
This is a very small observational study (15 people) that only looks at short-term balance changes. It cannot prove cause and effect, and results may not apply to everyone with stiff knee gait.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.