Gene clues to Crohn's disease risk explored in new study
NCT ID NCT07387172
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed study looked at whether certain gene variations (BAFF) are linked to the risk and features of Crohn's disease. Researchers compared 824 people with and without the disease. The goal was to better understand the genetic factors involved, which could guide future research.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If this study finds a clear link, it could point toward new ways to predict or understand Crohn's disease risk.
- What could go wrong
- This is an observational genetic study, not a treatment trial. It cannot prove cause and effect, and results may not apply to other populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
824 people
The number who actually took part.
- Started
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Jan 2020
- Finished
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Dec 2024
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
There was no statistically significant difference in the gender ratio, average age, and proportion of smokers between CD group and normal control group. All study subjects are from the Zhejiang Han population who are not related by blood.
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * diagnosed CD based on comprehensive clinical, colonoscopy, histopathological, laboratory, and radiographic examination results Exclusion Criteria: * rheumatoid arthritis, systemic lupus erythematosus, intestinal tuberculosis, ischemic enteritis, radiation enteritis, tumors, etc
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
the Second Affiliated Hospital of Wenzhou Medical University
Wenzhou, Zhejiang, 325000, China
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Other studies related to the condition(s) this trial covers.
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