Gut bugs on the move? new study tracks Bacteria's journey to surgical wounds
NCT ID NCT03554148
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is observing 209 adults undergoing planned abdominal surgery to understand how bacteria might travel from the gut to cause surgical site infections. Researchers collect samples (skin, rectal, blood, and tissue biopsies) during surgery and use DNA sequencing to track bacterial movement. The goal is to see if bacterial DNA in the liver or lymph nodes is linked to later wound infections.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help identify ways to predict or prevent surgical site infections after abdominal surgery.
- What could go wrong
- This is an observational study, not a treatment trial. It will not directly test any new drug or intervention, so any insights may take years to translate into clinical practice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 209 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2017
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Consecutive patients undergoing elective visceral surgery. Mostly for oncological indications.
- Ages
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18 years and older
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Informed Consent * All Ages * All Gender * Elective Abdominal Surgery * Age \> 18 * All approached (laparoscopic, open) * All ethnic and sociodemographic backgrounds * Sufficient knowledge of the study language (German) Exclusion Criteria: * pregnant or lactating women * no operation performed (i.e. only planned) * insufficient knowledge of project language (German) * lack of informed consent * known colonization with multi-resistant bacteria (e.g. Methicillin-resistant Staphylococcus aureus (MRSA) or extended spectrum betalactamase (ESBL)) * known cirrhotic liver disease
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Inselspital, University Hospital Bern, Visceral Surgery Department
Bern, 3008, Switzerland
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