New study aims to find best combo therapy for stubborn back pain
NCT ID NCT07258927
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two manual therapy techniques—integrated neuromuscular inhibition and muscle energy—each combined with core stabilization exercises, in 60 adults with chronic mechanical low back pain. Participants receive treatment twice weekly for six weeks. The goal is to see which combination better reduces pain, improves mobility, and enhances quality of life.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Core stabilization exercises combined with either integrated neuromuscular inhibition technique or muscle energy technique
- What this could lead to
- If successful, this could show which manual therapy technique works best alongside core exercises for reducing pain and improving daily function in people with chronic low back pain.
- What could go wrong
- This is a small, early-stage trial with only 60 participants, so results may not apply to everyone. The treatments are behavioral and effects may vary widely between individuals.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2025
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Ages 18-65 * Diagnosed chronic mechanical low back pain (\>3 months) * Pain localized between T12 and gluteal fold * Ability to follow exercise instructions * Voluntary consent Exclusion Criteria: * Spine surgery history * Herniated disc with neurological deficit * Systemic neuromuscular or rheumatologic disease * Acute lumbar trauma * Pregnancy * Current participation in another clinical trial * Use of analgesics, muscle relaxants, or physiotherapy within the past 4 weeks
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Istanbul University-Cerrahpaşa, Graduate School / Doctoral Program
Istanbul, BAŞAKŞEHİR, 34490, Turkey (Türkiye)
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