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New study aims to uncover why some patients suffer more after colorectal surgery

NCT ID NCT07219160

Knowledge-focused Sponsor: University of Alabama at Birmingham Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 14, 2026 · Updated 2 times

Summary

This study looks at why some people have more pain than others after colorectal surgery. Researchers will test pain sensitivity, analyze blood for inflammation, and ask about emotional health and life stress. The goal is to find better ways to manage pain and prevent long-term discomfort.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could help doctors identify patients at higher risk for severe pain after colorectal surgery and tailor pain management strategies.
What could go wrong
This is an observational study, not a treatment trial. It aims to understand pain, not to test a new drug or cure. Results may not lead to immediate changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 128 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Aug 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients scheduled to undergo colorectal surgery

Ages

18 to 89 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participants scheduled for colorectal cancer surgery * Age between 18-65; 3) * Understanding verbal and written English Exclusion Criteria: * Concurrent medical conditions that could confound the interpretation of the data * Human immunodeficiency virus positive diagnosis * Cardiovascular or pulmonary disease * Systemic rheumatoid disease * Uncontrolled hypertension (i.e. SBP/DBP of \> 150/95 * Current illness accompanied by fever (body temperature \>38 °C) * Any other chronic pain conditions * Conditions resulting in altered nerve sensation * Hospitalization due to psychiatric illness within the last 6 months * Poorly controlled diabetes * History of stroke * History of seizures * Circulatory disorders such AS Raynauds' disease * History of drug or alcohol abuse.

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Conditions

The condition(s) this trial relates to.

Acute Pain Chronic Pain colorectal cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colorectal surgery

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.