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New drug AZD5492 enters human safety trials for autoimmune diseases

NCT ID NCT06916806

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 22 times

Summary

This early-stage study tests the safety of a new drug called AZD5492 in 72 adults with lupus, myositis, or rheumatoid arthritis. Participants receive either one or two doses of the drug and are monitored for side effects over about 6 months. The goal is to find a safe dose and understand how the drug moves through the body.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    RECRUITING

    Anniston, Alabama, 36207, United States

  • Research Site

    WITHDRAWN

    Birmingham, Alabama, 35233, United States

  • Research Site

    NOT_YET_RECRUITING

    La Jolla, California, 92037, United States

  • Research Site

    NOT_YET_RECRUITING

    Sacramento, California, 95817, United States

  • Research Site

    RECRUITING

    Iowa City, Iowa, 52242, United States

  • Research Site

    NOT_YET_RECRUITING

    Chapel Hill, North Carolina, 27599, United States

  • Research Site

    NOT_YET_RECRUITING

    Hamilton, Ontario, L8S 4K1, Canada

  • Research Site

    RECRUITING

    Sherbrooke, Quebec, J1G 2E8, Canada

  • Research Site

    RECRUITING

    Beijing, 100730, China

  • Research Site

    RECRUITING

    Shanghai, 200001, China

  • Research Site

    RECRUITING

    Wuhan, 430022, China

  • Research Site

    NOT_YET_RECRUITING

    Zhengzhou, 450052, China

  • Research Site

    RECRUITING

    Bordeaux, 33000, France

  • Research Site

    RECRUITING

    Montpellier, 34295, France

  • Research Site

    RECRUITING

    Nancy, 54035, France

  • Research Site

    RECRUITING

    Paris, 75013, France

  • Research Site

    RECRUITING

    Strasbourg, 67098, France

  • Research Site

    RECRUITING

    Toulouse, 31059, France

  • Research Site

    NOT_YET_RECRUITING

    Cologne, 50937, Germany

  • Research Site

    NOT_YET_RECRUITING

    Erlangen, 91054, Germany

  • Research Site

    NOT_YET_RECRUITING

    Magdeburg, 39120, Germany

  • Research Site

    RECRUITING

    Bunkyō City, 113-8655, Japan

  • Research Site

    RECRUITING

    Kita-gun, 761-0793, Japan

  • Research Site

    RECRUITING

    Kitakyushu-shi, 807-8555, Japan

  • Research Site

    RECRUITING

    Kyoto, 606-8501, Japan

  • Research Site

    RECRUITING

    Nagasaki, 852-8501, Japan

  • Research Site

    RECRUITING

    Amsterdam, 1105 AZ, Netherlands

  • Research Site

    WITHDRAWN

    Leiden, 2333, Netherlands

  • Research Site

    RECRUITING

    Mérida, 06800, Spain

  • Research Site

    RECRUITING

    Seville, 41010, Spain

  • Research Site

    RECRUITING

    Valladolid, 47012, Spain

  • Research Site

    RECRUITING

    Glasgow, G31 2ER, United Kingdom

  • Research Site

    RECRUITING

    London, SE5 9RS, United Kingdom

  • Research Site

    RECRUITING

    London, WC1E 6JF, United Kingdom

  • Research Site

    RECRUITING

    Southampton, SO16 6YD, United Kingdom

Conditions

Explore the condition pages connected to this study.