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Ancient gut therapy takes on allergies in new clinical trial

NCT ID NCT07626099

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether an Ayurvedic treatment that targets digestion and gut health can reduce allergy symptoms and immune markers in people with allergic rhinitis (hay fever). 104 adults aged 18-40 with confirmed allergies will receive either the Ayurvedic treatment plus standard care, or standard care alone. The main goal is to measure changes in immune markers and gut permeability over 4 weeks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 104 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2028

An estimate. Start dates often move.

Expected to finish

Dec 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

16 to 40 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

\*\*Inclusion Criteria:\*\* * Participants aged 18-40 years. * Clinical diagnosis of Allergic Rhinitis based on standard diagnostic criteria. * Positive skin prick test to relevant allergens. * Presence of active allergic rhinitis symptoms at the time of recruitment. * Willingness to participate and provide written informed consent. * Willingness to comply with study procedures, laboratory investigations, and follow-up assessments. \*\*Exclusion Criteria:\*\* * Severe systemic illness. * Immunodeficiency disorders. * Autoimmune diseases. * Chronic gastrointestinal disorders that may influence gut permeability parameters. * Other chronic inflammatory conditions that may influence immune response. * Long-term immunosuppressive therapy. * Systemic corticosteroid therapy. * Biologic therapy. * Use of medications known to significantly alter immune response or gut microbiota. * Use of antibiotics within the previous 3 months. * Use of probiotics within the previous 3 months. * Use of prebiotics within the previous 3 months. * Pregnancy. * Lactation. * Known food allergy or hypersensitivity to study medications. * Severe psychiatric illness. * Inability to comply with study procedures. * Current participation in another clinical trial.

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Conditions

The condition(s) this trial relates to.

allergic rhinitis Rhinitis, Allergic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The official record

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More trials for these conditions

Other studies related to the condition(s) this trial covers.