Lymphoma Patients' brain function under microscope after new cell therapy
NCT ID NCT04319237
First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 30 times
Summary
This study followed 60 adults with diffuse large B-cell lymphoma or transformed lymphoma who received commercial axi-cel therapy. Researchers measured changes in memory, attention, executive function, hand strength, and quality of life using surveys and cognitive tests. The goal was to better understand the real-world side effects of this treatment on brain function and daily living.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
axicabtagene ciloleucel (axi-cel)
What this could lead to
If successful, this study could help doctors better understand and manage the cognitive and emotional side effects of axi-cel therapy, improving patient support.
What could go wrong
This is an observational study with no new treatment being tested. It only measures outcomes in a small group (60 people) and cannot prove cause and effect.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.