Could an avocado pill help you lose weight and control blood sugar?
NCT ID NCT07354308
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This 16-week study tests whether an avocado-based dietary supplement (Metavo) can help overweight adults manage their weight and blood sugar. Sixty participants will take either the supplement or a placebo daily, and researchers will track changes in body weight, glucose levels, and other health markers. The goal is to see if this natural supplement offers a safe, supportive option for metabolic health.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Avocado dietary supplement (Metavo)
- What this could lead to
- If it works, this could point toward a natural supplement to help manage weight and blood sugar in overweight adults.
- What could go wrong
- This is a small, early-stage trial with only 60 participants. Results may not apply to everyone, and the supplement may show no benefit over placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
May 2025
- Expected to finish
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Jan 2026
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Be male or female * Be aged between 18 and 70 years of age * Be classified as overweight or obese with a BMI of ≥25.0 and ≤32 kg/m2. * Have a stable weight defined as \<10% change in body weight in three months prior to the study start date. * Willing to follow the provided diet and exercise guidelines. * Willing to not consume avocados throughout the trial and for two weeks prior to Baseline * Anyone who is generally healthy - does not live with any uncontrolled chronic disease. * Willing to stop any products, any prescription medication, or supplements that target weight management, blood sugar control, and/or aim to improve insulin during the test period. * Willing to avoid introducing any new products or any new forms of prescription medication or supplements that target weight management, blood sugar control, and/or aim to improve insulin during the test period. * Not currently partaking in another research study and will not be partaking in any other research study for the next 16 weeks and at any point during this study's duration. * Must have someone available to take front and side profiles of the torso. * Must have a smart phone or camera capable of taking photos of the torso. * Resides in the United States. Exclusion Criteria: * Anyone with diagnosed Type I or Type II diabetes. * Allergic to avocados * Anyone with any allergies or sensitivities to any of the study product ingredients. * Any women who are pregnant, breastfeeding, or trying to conceive * Anyone unwilling to follow the study protocol. * Has stopped using hormonal birth control in the past month. * Anyone with a history of substance abuse. * Anyone who is currently a smoker or has been a smoker in the past 6 months. * Anyone with chronic health conditions that could impact participation in the study, such as oncological, psychiatric, metabolic, hypertension, or cardiovascular disorders, cancer, autoimmune disease, HIV, Hepatitis B, and/or C, kidney and/or liver, gastrointestinal, gastroesophageal reflux, blood/bleeding disorders, gout, or mental health disorders. * Anyone who has had any major illness in the last 3 months. * Anyone who drinks heavily (i.e., 8 or more alcoholic drinks per week for women or 15 or more alcoholic drinks per week for men). * Current use of prescribed medications as listed below: Weight loss prescription medication (within 3 months of baseline). Anticoagulants and coagulants (within 4 weeks of baseline). * Anyone who has used any cannabis products (medical or recreational) in the past month.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Citruslabs
Las Vegas, Nevada, 89118, United States
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