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New Audio-Visual device may let children skip anesthesia during cancer treatment

NCT ID NCT03991156

Symptom relief Sponsor: Stanford University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether an audio-visual system called AVATAR can help children aged 3 to 10 stay still during radiotherapy without needing anesthesia. The system uses calming sounds and images to distract and relax the child. If it works, it could reduce the risks and stress associated with anesthesia for young cancer patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Audio-Visual Assisted Therapeutic Ambience in Radiotherapy (AVATAR) device
What this could lead to
If successful, this could offer a non-drug alternative to anesthesia for young children undergoing radiotherapy, reducing side effects and anxiety.
What could go wrong
This is a small, early-stage study (80 participants) and success depends on each child's cooperation. The device may not work for all children, and some may still need anesthesia.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

80 people

The number who actually took part.

Started

May 2019

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The age range of patients is 3-10 years old, and there is no discrimination on ethnic background in recruitment for this study.

Ages

3 to 10 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Pediatric patients ages 3-10 receiving radiotherapy qualify for enrollment. * The patient must speak English or Spanish. Exclusion Criteria: * If parent/guardian is unable to take part in helping to complete questionnaires * Patients with malignancies of the eye for which radiation is planned * Patients that do not speak English or Spanish

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anesthesia

Contacts and locations

Locations

  • Cincinnati Children's/UC Health Proton Therapy Center

    Cincinnati, Ohio, 45229, United States

  • Dana Farber Cancer Institute/Brigham & Women Children Hospital

    Boston, Massachusetts, 02215, United States

  • Indiana University

    Bloomington, Indiana, 47405, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21218, United States

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States

  • St. Jude Children Hospital

    Memphis, Tennessee, 38105, United States

  • St. Louis Children's Hospital

    St Louis, Missouri, 63110, United States

  • Stanford University

    Stanford, California, 94304, United States

  • University North Carolina

    Chapel Hill, North Carolina, 27599, United States

  • University of Minnesota

    Minneota, Minnesota, 55455, United States

  • University of Rochester School of Medicine

    Rochester, New York, 14642, United States

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