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New drug shows promise for managing rare mast cell disease

NCT ID NCT07255638

First seen Dec 15, 2025 · Last updated May 23, 2026 · Updated 16 times

Summary

This study follows 80 adults in Germany with indolent systemic mastocytosis whose symptoms are not well controlled by current treatments. Researchers will track how well avapritinib works in real-world settings over up to 24 months, focusing on quality of life and symptom control. The goal is to better understand the drug's effectiveness and the disease's natural history.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Charité Universitätmedizin Berlin, Klinik für Dermatologie, Venerologie und Allergologie

    RECRUITING

    Berlin, 10117, Germany

  • HNO-Gemeinschaftspraxis Wiesbaden, GEKA Gesellschaft für Experimentelle und Klinische Atemwegsforschung mbH, Zentrum für Rhinologie und Allergologie

    RECRUITING

    Wiesbaden, 65205, Germany

  • Helios Universitätsklinikum Wuppertal

    RECRUITING

    Wuppertal, 42283, Germany

  • Katholisches Klinikum Bochum

    RECRUITING

    Bochum, 44791, Germany

  • MVZ Klinikum Deggendorf

    RECRUITING

    Deggendorf, 94469, Germany

  • Universitats-Hautklinik Tubingen, Studienzentrum lmmundermatologie

    RECRUITING

    Tübingen, 72076, Germany

  • University Medical Center Goettingen - Georg August University of Goettingen

    RECRUITING

    Göttingen, 37075, Germany

  • Universitätsklinikum Carl Gustav Carus Dresden Klinik und Poliklinik für Dermatologie

    RECRUITING

    Dresden, 01307, Germany

Conditions

Explore the condition pages connected to this study.