New drug avapritinib tracked in real life for Hard-to-Control mast cell disease

NCT ID NCT07255638

First seen Dec 15, 2025 · Last updated May 08, 2026 · Updated 13 times

Summary

This study follows about 80 people in Germany who have indolent systemic mastocytosis (ISM) and are starting avapritinib as part of their normal care because other treatments haven't controlled their symptoms well enough. Researchers will track changes in quality of life and other health measures for up to 24 months. The goal is to see how well the drug works in real-world settings and to learn more about the disease itself.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Charité Universitätmedizin Berlin, Klinik für Dermatologie, Venerologie und Allergologie

    RECRUITING

    Berlin, 10117, Germany

  • HNO-Gemeinschaftspraxis Wiesbaden, GEKA Gesellschaft für Experimentelle und Klinische Atemwegsforschung mbH, Zentrum für Rhinologie und Allergologie

    RECRUITING

    Wiesbaden, 65205, Germany

  • Helios Universitätsklinikum Wuppertal

    RECRUITING

    Wuppertal, 42283, Germany

  • Katholisches Klinikum Bochum

    RECRUITING

    Bochum, 44791, Germany

  • MVZ Klinikum Deggendorf

    RECRUITING

    Deggendorf, 94469, Germany

  • Universitats-Hautklinik Tubingen, Studienzentrum lmmundermatologie

    RECRUITING

    Tübingen, 72076, Germany

  • University Medical Center Goettingen - Georg August University of Goettingen

    RECRUITING

    Göttingen, 37075, Germany

  • Universitätsklinikum Carl Gustav Carus Dresden Klinik und Poliklinik für Dermatologie

    RECRUITING

    Dresden, 01307, Germany

Conditions

Explore the condition pages connected to this study.