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Text message links may boost smoking quit rates — a primary care trial puts the idea to the test

NCT ID NCT07735286

Disease control Sponsor: University of Pennsylvania Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time

Summary

This trial tests whether integrating tobacco cessation tools into electronic health records can increase the number of smokers who receive a prescription for nicotine replacement therapy (NRT) like patches or gum. Researchers will compare a new workflow at one primary care clinic against usual care at another, involving about 4,800 adult patients. The goal is to see if automated text message links to counseling and NRT resources make it easier for doctors and patients to address smoking during routine visits.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
tobacco cessation counseling resources and nicotine replacement therapy (NRT) via text message links
What this could lead to
If successful, this approach could make it easier for primary care doctors to routinely offer smoking cessation tools like nicotine patches or gum to patients who smoke.
What could go wrong
This is a non-randomized, early-stage trial at two sites, so results may not apply broadly. The intervention relies on patients engaging with text message links, which may have limited uptake.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 4,800 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years or older * Patient at Penn Family Care or Edward Cooper Internal Medicine * Had an eligible scheduled or completed practice visit categorized as a new annual visit, return patient visit, return annual visit, or return patient sick visit * For the tobacco cessation intervention: Penn Family Care patient who had not previously completed the tobacco questionnaire * For the 30-day follow-up survey: Active smoker in the EHR as of the completed visit date or prescribed nicotine replacement therapy (NRT) between 3 days before and 30 days after the completed visit date * For the primary analysis: Active smoker in the EHR as of the completed visit date * For the primary analysis: Did not have an NRT prescription between 34 and 4 days before the completed visit date Exclusion Criteria: * None except as specified in inclusion criteria.

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Conditions

The condition(s) this trial relates to.

nicotine dependence Tobacco Use Tobacco Use Cessation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Tobacco use Tobacco use cessation

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  2. A doctor treating you

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Other studies related to the condition(s) this trial covers.