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Eye-Opening study: pupil test may gauge pain in confused ICU patients

NCT ID NCT05811208

Knowledge-focused Sponsor: St. Anne's University Hospital Brno, Czech Republic Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

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Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
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Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a device that measures pupil changes (automated pupillometry) can help assess pain in intensive care patients who are confused or delirious after surgery. Pain is hard to evaluate in these patients because they cannot communicate clearly. The study enrolled 49 adults and compared pupil measurements with standard pain scales to see if they matched. Results may improve pain management for vulnerable ICU patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

49 people

The number who actually took part.

Started

May 2023

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

surgical patinets admited to the ICU

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * patient after surgery * possibility to perform CAM - ICU test (patients with Richmond Agitation-Sedation Scale -2 to +2) Exclusion Criteria: * eye diseases * brain injury * stroke * epilepsy * neuromuscular diseases

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Conditions

The condition(s) this trial relates to.

delirium Pain Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Delirium Pain, postoperative

Contacts and locations

Locations

  • St. Anne's University Hospital in Brno

    Brno, Czech Republic, 60200, Czechia

More trials for these conditions

Other studies related to the condition(s) this trial covers.