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Ear acupressure shows promise for PMS relief in students

NCT ID NCT06981533

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether auricular acupressure (pressing points on the ear) can reduce symptoms of premenstrual syndrome (PMS) in female college students. 66 participants received either real or sham acupressure over 8 weeks. Researchers measured changes in PMS symptoms and quality of life using standard questionnaires.

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Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

66 people

The number who actually took part.

Started

Apr 2025

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 25 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female students aged 18 to 25 with active menstrual cycles and menstrual periods ranging from 25 to 35 days. * Participants must be able to accurately recall the start date of their most recent menstruation cycle. * Participants must exhibit symptoms of Premenstrual Syndrome (PMS) and meet the diagnostic criteria for PMS as defined by the American College of Obstetricians and Gynecologists (ACOG) 2014. * Participants must not have any chronic conditions, including respiratory diseases (e.g., asthma, pneumonia, chronic obstructive pulmonary disease), thyroid disorders, autonomic nervous system disorders, hypertension, coronary artery disease, or diabetes, as determined through clinical examination, medical history, and prior medical records. * Participants must not have severe psychological stress (a score lower than 27 on the Perceived Stress Scale - PSS-10). * Participants must be mentally alert and in good contact with the researcher. * Participants must voluntarily consent to participate in the study. * Participants must not have prior knowledge of auricular acupuncture or auricular acupressure. Exclusion Criteria: * Infection or lesions in the ear area (e.g., scars, tears, abrasions). * Menstrual cycles shorter than 25 days or longer than 35 days. * Participants unable to recall the start date of their most recent menstruation cycle. * Participants diagnosed with gynecological conditions such as uterine fibroids, endometriosis, or ovarian cysts, based on medical history and recent abdominal ultrasound results (within the past 6 months). * History of abortion, currently pregnant, or planning to become pregnant during the study period. * Use of antidepressants and/or antipsychotic drugs, hormone supplements, oral contraceptives, or intrauterine devices within the past two months. * Current or past psychiatric disorders. * Participants with severe psychological stress (a score between 27 and 40 on the PSS-10). * Unstable mental state, sensory impairments (e.g., hearing, vision, speech), or cognitive disabilities. * Previous auricular acupressure, acupuncture, or other forms of acupuncture for PMS treatment within the last 6 months. * Use of medication for PMS symptom relief during the study period.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of Traditional medicine - University of Medicine and Pharmacy at Ho Chi Minh City

    Ho Chi Minh City, Ho Chi Minh City, 700000, Vietnam

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