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Brain imaging study seeks clues to childhood epilepsy

NCT ID NCT04569708

Knowledge-focused Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled This study
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 3 times

Summary

This study looked at how sounds played during sleep affect brain waves and memory in children with Rolandic epilepsy. Researchers used brain scans (MRI, MEG/EEG) to understand which brain circuits are involved. The goal was to find new treatment ideas for this type of childhood epilepsy. The study included 30 children aged 4-18 with and without epilepsy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Started

Jan 2021

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

4 to 18 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Clinical diagnosis of childhood epilepsy with centrotemporal spikes (CECTS)or Rolandic epilepsy by child neurologist * Ages 4-18 years * Has an EEG with sleep activated centrotemporal spikes * Has had at least 1 focal motor or generalized seizure Exclusion Criteria: * Has abnormal brain MRI * Has other unrelated neurological disease * Unable to have an MRI/MEG due to claustrophobia, history of frequent vomiting, permanent metal in body (braces), or over MRI weight limit: 350lbs

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Conditions

The condition(s) this trial relates to.

epilepsy Epilepsy, Rolandic self-limited epilepsy with centrotemporal spikes

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Centrotemporal epilepsy Centrotemporal; eeg spikes, epilepsy of childhood Epilepsy Epilepsy; seizure Rolandic epilepsy Rolandic epilepsy, benign

Contacts and locations

Locations

  • Athinoula A. Martinos Center Biomedical Imaging

    Charlestown, Massachusetts, 02129, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.