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Mind over muscle: new study tests if focus cues boost knee rehab

NCT ID NCT07384858

Symptom relief Sponsor: Istanbul University - Cerrahpasa Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 19, 2026 · Updated 2 times

Summary

This study looks at whether telling people to focus on their muscles (internal focus) or on an external object (external focus) during knee exercises leads to better strength and less pain. Researchers will enroll 36 adults with patellofemoral pain syndrome and track their progress over 6 weeks. The goal is to find the best way to give exercise instructions for faster recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
attentional focus strategies (internal vs. external cues during exercise)
What this could lead to
If successful, this could show that simple changes in how you think during exercise can improve knee strength and reduce pain, leading to better rehab programs.
What could go wrong
This is a small, early-stage study with only 36 participants, so results may not apply to everyone. The intervention is just a different way of giving exercise instructions, so any benefit is likely modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

36 people

The number who actually took part.

Started

Feb 2026

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged between 18 and 45 years. * Diagnosed with patellofemoral pain syndrome (PFPS). * Anterior or retropatellar knee pain persisting for at least four weeks with a VAS score \> 3. * Pain exacerbated by at least two functional activities (e.g., squatting, stair climbing, prolonged sitting). * Willing to regularly participate in the 6-week program throughout the study period. Exclusion Criteria: * History of patellar subluxation or dislocation. * Anterior or posterior cruciate ligament insufficiency. * Lower extremity fractures. * Neurological or systemic musculoskeletal disorders. * Rheumatoid arthritis or other inflammatory joint diseases. * History of knee surgery, meniscal injury, or any other underlying musculoskeletal condition that would prevent the participant from performing the exercises. * Pregnancy or postpartum period. * Participation in a similar exercise program within the last 3 months. * Radiographic evidence of osteoarthritis classified as Kellgren-Lawrence grade 2 or higher.

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Conditions

The condition(s) this trial relates to.

patellofemoral pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Patellofemoral pain, PFP

Contacts and locations

Locations

  • Istanbul University-Cerrahpasa

    Istanbul, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.