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New drug combo targets rare cancer that resists standard treatment

NCT ID NCT06528769

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 29 times

Summary

This study tests whether combining two drugs—ATRA and cemiplimab—can shrink or slow advanced leiomyosarcoma, a rare soft-tissue cancer. About 16 adults whose cancer worsened after standard chemotherapy will receive ATRA pills for 3 days before each cemiplimab infusion, then cemiplimab alone until the disease progresses or side effects become unacceptable. The main goal is to see how many patients respond, with secondary focus on how long the cancer stays controlled.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ohio State University Comprehensive Cancer Center

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact Email: •••••@•••••

    Contact

Conditions

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