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Can a statin tame a cancer protein? early trial hints at possibility

NCT ID NCT03560882

First seen May 07, 2026 · Last updated May 23, 2026 · Updated 6 times

Summary

This early-phase trial is testing whether atorvastatin, a widely used cholesterol medication, can reduce levels of a faulty protein called p53 in people with various cancers, including solid tumors and acute myeloid leukemia. About 50 participants will take the drug for 1 to 4 weeks before their planned surgery or treatment. The main goal is to measure changes in the mutant p53 protein, not to treat the cancer directly, so this study is focused on gathering knowledge rather than providing a cure.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Kansas Cancer Center - CRC

    Fairway, Kansas, 66205, United States

Conditions

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