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New hope for rare tumors: drug duo shows promise

NCT ID NCT03074513

First seen Nov 01, 2025 · Last updated Jun 16, 2026 · Updated 28 times

Summary

This study tests whether combining two drugs, atezolizumab and bevacizumab, can shrink or control rare solid tumors. About 133 adults with cancers like appendix, anal, cervical, or mesothelioma will receive the drugs intravenously. The goal is to see if this immunotherapy approach works better than current treatments for these hard-to-treat cancers.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

The condition(s) this trial relates to.

Adenoma, Islet Cell anal squamous cell carcinoma appendix adenocarcinoma cervical squamous cell carcinoma cutaneous neuroendocrine carcinoma human papillomavirus-related penile squamous cell carcinoma human papillomavirus-related squamous cell carcinoma malignant peritoneal mesothelioma malignant pleural mesothelioma Mesothelioma, Malignant mucinous adenocarcinoma nasopharyngeal carcinoma nasopharyngeal neoplasm neuroendocrine carcinoma pancreatic neuroendocrine tumor squamous cell carcinoma of penis vaginal squamous cell carcinoma vulvar squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.