New drug combo aims to supercharge immune attack on tough cancers
NCT ID NCT05082259
First seen Feb 14, 2026 · Last updated May 21, 2026 · Updated 11 times
Summary
This early-phase trial tests a new drug (ASTX660) combined with an immunotherapy (pembrolizumab) in people with advanced solid tumors, including triple-negative breast cancer and cervical cancer. The goal is to see if the combination is safe and can help the immune system recognize and kill cancer cells more effectively. About 61 participants will take part across multiple centers.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cambridge University Hospitals NHS Trust
RECRUITINGCambridge, CB2 0QQ, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Royal Marden NHS Foundation Trust - Drug Development Unit
RECRUITINGSutton, SM2 5PT, United Kingdom
Contact Phone: •••-•••-••••
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The Royal Marsden NHS Foundation Trust - Breast Unit
RECRUITINGSutton, SM2 5PT, United Kingdom
Contact Email: •••••@•••••
Conditions
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