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New tool aims to predict chemo risks for seniors

NCT ID NCT00477958

Knowledge-focused Sponsor: City of Hope Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a geriatric assessment tool—looking at thinking, memory, daily activities, and emotional well-being—can predict serious side effects from chemotherapy in older adults with cancer. Over 1,000 patients completed questionnaires and cognitive tests before and after treatment. The goal is to help doctors tailor cancer care for seniors.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors better predict which older patients are at risk for serious side effects from chemotherapy, leading to more personalized treatment plans.
What could go wrong
This is an observational study, not a treatment trial. The assessment tool may not accurately predict toxicity, and results may not apply to all older patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

1,062 people

The number who actually took part.

Started

Dec 2006

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 to 120 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

DISEASE CHARACTERISTICS: * Pathologically confirmed cancer * Receiving chemotherapy for either adjuvant treatment or metastatic disease prior to beginning a new chemotherapy regimen PATIENT CHARACTERISTICS: * Must be able to understand English PRIOR CONCURRENT THERAPY: * See Disease Characteristics * No prior enrollment in this trial * No concurrent enrollment on a phase I clinical trial

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Conditions

The condition(s) this trial relates to.

cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cognitive/functional effects Psychosocial effects of cancer and its treatment Unspecified adult solid tumor, protocol specific

Contacts and locations

Locations

  • Case Comprehensive Cancer Center

    Cleveland, Ohio, 44106-5065, United States

  • Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center

    Orange, California, 92868, United States

  • City of Hope Medical Center

    Duarte, California, 91010-3000, United States

  • James P. Wilmot Cancer Center at University of Rochester Medical Center

    Rochester, New York, 14642, United States

  • Memorial Sloan-Kettering Cancer Center

    New York, New York, 10065, United States

  • Tower Cancer Research Foundation

    Beverly Hills, California, 90211, United States

  • Wake Forest University Comprehensive Cancer Center

    Winston-Salem, North Carolina, 27157-1096, United States

  • Yale Cancer Center

    New Haven, Connecticut, 06520-8028, United States

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Other studies related to the condition(s) this trial covers.