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New drug aims to shrink hard-to-treat stomach and pancreatic tumors

NCT ID NCT07488676

First seen Mar 27, 2026 · Last updated May 23, 2026 · Updated 11 times

Summary

This study tests a new drug called ASP546C in people with advanced stomach, gastroesophageal junction, pancreatic, or other solid tumors that have a specific protein (CLDN18.2). The drug is given as an infusion every 3 weeks. The study has two parts: Part 1 finds the best dose in stomach/GEJ cancer patients, and Part 2 tests that dose in pancreatic and other tumor types. The goal is to see if the drug can shrink tumors and to check for side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Next Oncology - Austin

    RECRUITING

    Austin, Texas, 78758, United States

  • Next Oncology - Dallas

    RECRUITING

    Irving, Texas, 75039, United States

  • Next Oncology - Houston

    RECRUITING

    Houston, Texas, 77054, United States

  • START Los Angeles

    RECRUITING

    Los Angeles, California, 90025, United States

  • START Midwest

    RECRUITING

    Grand Rapids, Michigan, 49546, United States

  • START Mountain Region

    RECRUITING

    West Valley City, Utah, 84119, United States

  • START New York

    RECRUITING

    Lake Success, New York, 10042, United States

  • START San Antonio

    RECRUITING

    San Antonio, Texas, 78229, United States

Conditions

Explore the condition pages connected to this study.