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New drug targets tumor protein in first human tests

NCT ID NCT07287995

First seen Jan 06, 2026 · Last updated May 23, 2026 · Updated 27 times

Summary

This early study tests a new drug, ASP2998, that attaches to a protein called TROP2 found on many solid tumors to attack cancer cells. It is given alone or with standard treatments like pembrolizumab or carboplatin. The study includes adults with advanced bladder, lung, stomach, or breast cancers that have spread or cannot be removed by surgery. The main goals are to check safety and find the right dose.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • John Theurer Cancer Center at Hackensack University Medical Center

    RECRUITING

    Hackensack, New Jersey, 07601, United States

  • NEXT Virginia

    RECRUITING

    Fairfax, Virginia, 22031, United States

  • National Cancer Center Hospital

    RECRUITING

    Chuo-ku, Tokyo, Japan

  • National Cancer Center Hospital East

    RECRUITING

    Kashiwa-shi, Chiba, Japan

  • START New York Long Island

    RECRUITING

    New Hyde Park, New York, 11042, United States

  • Tennessee Oncology

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • The Cancer Institute Hospital of JFCR

    RECRUITING

    Koto-ku, Tokyo, Japan

Conditions

Explore the condition pages connected to this study.