Can a Stress-Relieving herb boost your skin and hair?
NCT ID NCT07215689
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a daily 300 mg capsule of KSM-66 Ashwagandha, an herbal supplement, can improve skin and hair health in 50 healthy adults over 12 weeks. Participants are randomly assigned to receive either the supplement or a placebo, and neither they nor the researchers know who gets what. The goal is to see if reducing stress with ashwagandha leads to measurable improvements in skin moisture and hair density.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- KSM-66 Ashwagandha (ashwagandha root extract) dietary supplement
- What this could lead to
- If it works, this could provide a natural option to improve skin and hair health by reducing stress-related damage.
- What could go wrong
- This is a small, early-stage trial with only 50 healthy people. Results may not apply to everyone, and supplements are not regulated like drugs.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2025
- Expected to finish
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Dec 2025
An estimate. End dates often move.
- Lead sponsor
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A research network
The lead sponsor is a research network or cooperative group.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Healthy adult men and women participants ≥ 18 years and ≤60 years of age. 2. Willingness to follow the protocol requirements as evidenced by written informed consent. 3. Participants who were on consistent dietary, hair, and skin product 3 months prior to start of the study and are willing to follow the same during the study. 4. Participants who agree not to use any medication (prescription and over the counter), including vitamins and minerals, during or before the course of this study. 5. Participants with mild to moderate hair loss classified as the Norwood-Hamilton type II, III, IV and V in males and Ludwig type I and II in females. 6. Willing to come for all follow-up visits. 7. Participants who agree not to cut hair for the entire duration of the study. 8. Participants willing to undergo Trichoscan evaluation and not to wash their hair 48 hours before the visit. 9. Participants or LAR can and willing to give meaningful, written informed consent prior to participation in the trial, in accordance with regulatory requirements. 10. Participants who agree to take investigational product (i.e., Till Day 90 ± 4 ± 4). Exclusion Criteria: 1. Participants having any clinically significant medical history, medical finding including rosacea, eczema, psoriasis, and atopic dermatitis or an on-going medical or psychiatric condition exists which in the opinion of the Investigator could jeopardize the safety of the subject, impact validity of the study results or interfere with the completion of study according to the protocol. 2. Participants on any medication or supplement for hair loss, including finasteride, any other 5 α-reductase inhibitor, minoxidil, steroids, or hormonal products, during the 3 months prior to study commencement. 3. Participants having a history of hypersensitivity reactions (i.e., allergic or oversensitivity to study medication). 4. Participants who have undergone or plan to undergo hair transplantation surgery during the study period. 5. Participants with facial skin cancer. 6. Participants with sunburn, moderate to pronounced suntan, uneven skin tones, tattoos, scars or other disfiguration, dilated vessels or other conditions on the test area that might influence the test results. 7. Participants with severe seborrheic dermatitis, alopecic disease, except for androgenic alopecia, and scalp disorders, such as scalp psoriasis and infection. 8. Participants who have participated in a clinical study during the preceding 180 days. 9. Participants having eating disorders (i.e., bulimia, psychogenic eating disorders, etc.). 10. Pregnant and lactating females 11. Participants with alcohol addiction or persistent abuse of drugs of dependence.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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San Francisco Research Institute
RECRUITINGSan Francisco, California, 94132, United States
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