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New hope for brain metastases: drug combo targets hard-to-treat breast cancer

NCT ID NCT07136428

First seen Nov 16, 2025 · Last updated Jun 13, 2026 · Updated 26 times

Summary

This study tests a new drug, asciminib, combined with trastuzumab in 42 adults with HER2+ breast cancer that has spread to the brain. Participants must have tried at least one prior treatment, including T-DXd and tucatinib. The goal is to see if the combination can shrink brain tumors and control the cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

HER2 positive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.