New hope for brain metastases: drug combo targets hard-to-treat breast cancer

NCT ID NCT07136428

First seen Nov 16, 2025 · Last updated Jun 13, 2026 · Updated 26 times

Summary

This study tests a new drug, asciminib, combined with trastuzumab in 42 adults with HER2+ breast cancer that has spread to the brain. Participants must have tried at least one prior treatment, including T-DXd and tucatinib. The goal is to see if the combination can shrink brain tumors and control the cancer.

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Contacts and locations

Study contacts

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Conditions

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