Stiff arteries may reveal Who's skipping blood pressure pills
NCT ID NCT07207226
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at 60 adults with resistant hypertension—high blood pressure that doesn't improve even with multiple medications. Researchers measure artery stiffness using a simple, non-invasive test to see if it can help identify patients who aren't taking their drugs as prescribed. The goal is to better understand treatment adherence and improve heart health outcomes.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2024
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 90 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients between 18-90 years of age in both sexes, diagnosed with resistant hypertension. * \- Resistance Hypertension defined as - * Blood pressure at consultation \> 140 and/or 90 mmHg and/or 24h-ABPM (Ambulatory Blood Pressure Assessment) and/or in Home blood pressure measurement (HBPM) \> 130 and/or 80 mmHg despite taking three or more different classes of antihypertensive drugs at optimal doses, including a diuretic, on the day of screening irrespective of the BP on the day of the visit. * Any office BP, ABPM or HBPM values in patients taking four or more different classes of antihypertensive drugs at optimal doses, including a diuretic. * Patients scheduled for arterial stiffness assessment as a part of routine treatment. * Patients eligible or affiliated with a social security scheme. * Patients who provide written informed consent for participation. Exclusion Criteria: * \- Inability to express consent to the study * Persons subject to a judicial safeguard measure, under guardianship or curatorship. * Patients with skin lesions (severe eczema, wounds, etc.) on the chest or neck that do not allow the application of the protective skin film on the area of interest; Allergies to the adhesive film. * Subjects not affiliated with social security or an equivalent scheme. * Linguistic incapacity or psychic refusal to read the information. * Diseases carrying out a life -expectancy \<1 year according to clinical judgment * Pregnant women (because of physiological hemodynamic changes in BP and stiffness during pregnancy) * Arrhythmias: current AC/FA, high degree BAV. * Persons subject to a period of exclusion for another research * Foreseen inability to attend scheduled visits
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hopital Georges pompidou
Paris, Île-de-France Region, 75015, France
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Other studies related to the condition(s) this trial covers.
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