New hope for millions of kids: easier treatment for a devastating parasitic disease
NCT ID NCT06698510
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to see how well a new, child-friendly version of the drug praziquantel works to control schistosomiasis in preschool-aged children (2 to 5 years old) in parts of Kenya, Côte d'Ivoire, and Uganda. About 18,500 children will receive the medicine through existing public health programs. The goal is to find the best way to deliver the drug to this age group, who are often missed in current treatment campaigns.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 18,500 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2024
- Expected to finish
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Mar 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
* Study population receiving intervention: All eligible preschool-aged children (2-5 years) from pre-selected study areas for small-scale implementation present at the day of the treatment campaign, will be accessed and treated with arpraziquantel by one of the two selected platforms depending on the assignment of the area. * Study population of post-distribution social science study: Subsamples of parents of preschool-aged children of the respective implementation areas, community stakeholders involved in social mobilization and distribution, health workers and programmatic staff involved in training, social mobilization and distribution.
- Ages
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24 to 59 months
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
* Living in the designated implementation area since at least 6 months * Aged between 24 - 59 months * Informed consent available * No acute or chronic illness and/or inability to take oral medication * No reported history of seizures * No known allergic response to praziquantel
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
7 sites in 3 countries. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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African Institute for Health and Development (AIHD)
NOT_YET_RECRUITINGNairobi, Kenya
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Kenya Medical Research Institute (KEMRI), Eastern and Southern Africa Centre of International Parasite Control (ESACIPAC)
NOT_YET_RECRUITINGNairobi, Kenya
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Makerere University, Department of Sociology and Anthropology
NOT_YET_RECRUITINGKampala, Uganda
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Programme National de Lutte Contre les Maladies Tropicales Négligées à Chimiothérapie Préventive (PNLMTN-CP), Ministère de la Santé, de l'Hygiène Publique et de la Couverture Maladie Universelle (MSHPCMU)
RECRUITINGAbidjan, Côte d’Ivoire
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Université Félix Hophouët-Boigny (UFHB), Département de sociologie
RECRUITINGAbidjan, Côte d’Ivoire
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Université Félix Hophouët-Boigny (UFHB), UFR Biosciences
RECRUITINGAbidjan, Côte d’Ivoire
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Vector Borne & Neglected Tropical Disease Control Division, Ministry of Health
NOT_YET_RECRUITINGKampala, Uganda
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Other studies related to the condition(s) this trial covers.
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- New study tracks hidden infections in migrants
- Egyptian schistosomiasis study launches to map disease hotspots