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Sniffing away sickness: aromatherapy tested for chemo nausea

NCT ID NCT07209501

Symptom relief Sponsor: Singapore General Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tests whether aromatherapy inhaler sticks can reduce nausea and vomiting in 30 patients receiving chemotherapy as part of a stem cell transplant. Participants use the inhaler every four hours and whenever they feel sick. Half get essential oils, half get a placebo (jojoba oil only). The study mainly checks if this approach is practical and acceptable, and also tracks nausea severity and vomiting episodes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
aromatherapy inhaler with essential oils
What this could lead to
If it works, this could offer a simple, drug-free way to ease nausea and vomiting during chemotherapy for stem cell transplant patients.
What could go wrong
This is a very small pilot study (30 people) focused on feasibility, not proof of effectiveness. The results may not apply to all patients or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2025

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 99 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * At least 21 years and older * Able to provide informed consent * Admitted for autologous stem cell transplant receiving melphalan conditioning chemotherapy regime * Willing to have interviews audio-recorded Exclusion Criteria: * Currently using essential oils of any form (e.g. diffuser, topical application, * Known sensitivity/ allergy to essential oils * Any olfactory impairments (i.e. conditions that impair or alter sense of smell - for example, allergic rhinitis, chronic lung disease, blocked nose)

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Conditions

The condition(s) this trial relates to.

chemotherapy-induced toxicity plasma cell myeloma Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chemotherapy-induced nausea and vomiting (CINV)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Singapore General Hospital

    Singapore, 169608, Singapore

More trials for these conditions

Other studies related to the condition(s) this trial covers.