Arnica tested for wisdom tooth recovery: natural relief or sugar pill?
NCT ID NCT03944629
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether a homeopathic remedy called Arnica montana (SinEcch™) can reduce swelling and pain after having wisdom teeth removed. Fifty-three adults took either Arnica or a placebo (sugar pill) before and after surgery. Researchers measured facial swelling and pain levels over several days to see if the herb made a difference.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Arnica montana (homeopathic remedy)
- What this could lead to
- If it works, this could offer a natural option to reduce swelling and pain after dental surgery.
- What could go wrong
- This is a small, completed trial with only 53 participants. Homeopathic remedies are highly diluted and often show no effect beyond placebo.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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53 people
The number who actually took part.
- Started
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Jan 2018
- Finished
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Jun 2022
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 40 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Subjects of either sex and of any race from the ages of 18 to 40 years. * Subjects for whom a decision has been made to extract 4 third molars, and who have at least 2 of third molar teeth classified as full or partially bony impacted in the mandible, and they will be evaluated to have at least 2 of third molar teeth classified as erupted or impacted (full or partially bony) in the maxilla under local anesthesia alone, local anesthesia and sedation, or local anesthesia and general anesthesia, all in an outpatient setting. 1. Full/complete bony: The entire tooth is below the level of the alveolar bone. The tooth is completely encased in bone so that when the gingiva is cut and reflected back, the tooth is not seen. Bone removal (large amounts) together with root sectioning will be needed to remove the tooth. 2. Partial bony: A portion of the height of the contour of the tooth is below the level of the alveolar bone. The superficial portion of the tooth is covered only by soft tissue, but the height of the tooth's contour is below the level of the surrounding alveolar bone. * Subjects must be physically able to tolerate conventional surgical procedures (ASA I/II). * Subjects must agree to follow the study protocol as shown by signing the informed consent form. Exclusion Criteria: * Subjects who are known to be pregnant or think they may be pregnant. (A urine pregnancy test will be performed on female subjects at Day 0 - Visit 1. Subjects testing positive will be excluded from study participation.) * Subjects with skeletal immaturity as determined by the medical history. * Subjects with self-reported current or history of substance abuse. * Subjects who are currently receiving any anti-inflammatory or pain medication chronically, or they suffer from a chronic pain condition. * Subjects with an allergy to Vicodin (or its constituents, acetaminophen and hydrocodone). * Subjects who are diagnosed with fibromyalgia. * Allergy to ragweed and other related plants. * Subjects with an allergy to hypromellose. * Non-English speaking patients
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Tufts University School of Dental Medicine Department of Oral and Maxillofacial Surgery
Boston, Massachusetts, 02111, United States
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