Arm workouts may boost leg oxygen in PAD patients, study finds
NCT ID NCT06491810
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 26 people with peripheral arterial disease (PAD) to see how arm exercise changes oxygen levels in their leg muscles. Participants used an arm ergometer while a sensor measured calf oxygen saturation. The goal was to understand why arm training can improve leg function without causing leg pain during exercise.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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26 people
The number who actually took part.
- Started
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Jul 2024
- Finished
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Mar 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with peripheral artery disease
- Ages
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45 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. aged ≥ 50 years; 2. with PAD confirmed by clinical diagnosis and ankle-brachial index (ABI) \< 0.90 in one or both limbs; 3. experiencing symptoms of intermittent claudication (IC) during walking; 4. with a body mass index (BMI) not exceeding 30 kg/m²; 5. with medical clearance to participate in the project; 6. presenting calf skinfold thickness less than 20 mm due to interference of adiposity with the light penetration of the NIRS probe and finger oxygen saturation \> 95% to ensure that impaired pulmonary gas exchange does not affect the calf oxygen saturation measurements.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University Nove de Julho
São Paulo, São Paulo, 01525-000, Brazil
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