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New mapping technique aims to prevent arm swelling after breast cancer surgery

NCT ID NCT00572481

Disease control Sponsor: University of Arkansas Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a technique called axillary reverse mapping during breast cancer surgery. Doctors inject a radioactive tracer and blue dye to map the arm's lymph drainage, hoping to avoid damaging those vessels and reduce the risk of lymphedema (arm swelling). The study involves 1,000 participants and will track swelling for one year after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Axillary reverse mapping procedure using technetium-99m sulfur colloid and blue dye
What this could lead to
If successful, this technique could reduce the risk of lymphedema after breast cancer surgery, improving long-term quality of life.
What could go wrong
This is a phase 2 study, so results are still preliminary. The technique may not significantly lower lymphedema risk, and there are standard surgical risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

About 1,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2007

Expected to finish

Nov 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18-100 years old * Not pregnant or breastfeeding * Breast cancer requiring lymph node evaluation for the ipsilateral or contralateral breast OR prophylactic mastectomy * Willing participation following an informed consent process Exclusion Criteria: * Patient \< 18 y/o or \> 100 y/o * Pregnant or breastfeeding * If a pregnant female should be diagnosed with breast cancer an exception would be considered on a case to case basis.

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Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cancer of the breast

Contacts and locations

Locations

  • University of Arkansas For Medical Sciences

    Little Rock, Arkansas, 72205, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.