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Apple watch could spot hidden heart condition in seniors

NCT ID NCT05686330

Diagnosis Sponsor: Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC) Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether an Apple Watch can detect atrial fibrillation (a heart rhythm problem) faster than usual methods in people aged 65 and older with high stroke risk. Over 400 participants wore the watch, which uses light sensors and an ECG to check heart rhythm. The goal was to see if the watch leads to quicker diagnosis and treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Apple Watch with photoplethysmography (PPG) and ECG functions
What this could lead to
If successful, this could show that smartwatches help detect atrial fibrillation earlier in high-risk people, potentially preventing strokes.
What could go wrong
The trial is small and completed; results may not apply to everyone. Smartwatch detection may lead to false alarms or unnecessary worry.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

436 people

The number who actually took part.

Started

Nov 2022

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 65 years * Chadsvasc score ≥2 for men and ≥ for women at the time of eligibility screening * Written informed consent as documented by signature from the participant * Possession of iPhone (6S or later) Exclusion Criteria: * Diagnosis of atrial fibrillation or atrial flutter * Currently on anticoagulation therapy * Cardiac implanted electronic device (pacemaker, ICD) * Smartwatch cannot be worn due to comprehensible reasons (allergic reactions, wounds, amputations, other) * Significant mental or cognitive impairment

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Conditions

The condition(s) this trial relates to.

Arrhythmias, Cardiac atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Atrial fibrillation

Contacts and locations

Locations

  • Cardiology Center of the Netherlands

    Amsterdam, North Holland, Netherlands

  • Spaarne Gasthuis

    Haarlem, North Holland, 2035 RC, Netherlands

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