New supplement aims to curb cravings and emotional eating
NCT ID NCT07621393
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a dietary supplement called DNF-10 can help healthy adults manage their appetite and reduce emotional eating. Fifty volunteers will take either DNF-10 or a placebo for a period, then switch, so everyone gets both. Researchers will track snacking, food-related anxiety, and hunger to see if the supplement makes a difference.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- DNF-10 (a dietary supplement)
- What this could lead to
- If it works, this could point toward a natural supplement to help people control cravings and emotional eating.
- What could go wrong
- This is a very early pilot study in healthy people, not those with obesity or eating disorders. The effects may be small or not work at all.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2026
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 50 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Healthy men and women aged 20 to 50 years. * Body Mass Index (BMI) of 18.5-24.9 kg/m² or 25.0-29.9 kg/m². * Stable use of permitted medications and/or dietary supplements during the study. * Individuals willing to maintain their usual dietary and physical activity habits throughout the study. * Subjects capable of understanding and complying with the study procedures. * Subjects who have signed the informed consent form. * Female participants must meet one of the following conditions: 1. Women with no potential for pregnancy, defined as women who have undergone surgical sterilization or who are postmenopausal. 2. Women of childbearing potential who use a highly effective contraceptive method (hormonal contraception, intrauterine device, condoms, male partner sterilization \[vasectomy\], or complete sexual abstinence) while participating in the study. Exclusion Criteria: * Individuals with known eating behavior disorders (verified using the Spanish version of the Adult Eating Behavior Questionnaire, AEBQ). * Subjects with a body weight gain or loss ≥10% within the previous 3 months. * Treatment with medications or dietary supplements for weight loss, satiety, or glucose control. * Individuals consuming protein powders or dietary supplements related to the objectives of the study. * Participants receiving active treatment with GLP-1 receptor agonists or similar agents. * Participants taking medications or dietary supplements that, in the investigator's opinion, may interfere with the study objectives (e.g., affecting appetite), pose a safety risk, or confound the interpretation of the study results. * Depression or anxiety disorders that affect appetite. * High coffee consumption (more than 4 cups per day). * Smokers (more than 5 cigarettes per week), smoking during study assessment days, and/or drug abuse. * History of bariatric surgery within the last 3 years. * Low iron levels requiring treatment. * Individuals with renal or endocrine diseases (including diabetes). * Untreated or unstable hyperthyroidism, suicidal ideation, bipolar disorder, or evidence of any untreated or unstable neurological disorder. * Conditions or diseases that, in the investigator's judgment, may be worsened by participation in the study or may jeopardize the conduct of the study. * Presence of infectious diseases at the time of study inclusion (participants may be included 1 month after resolution of the illness). * Severely immunocompromised participants (transplant recipients, individuals treated with anti-rejection medications or steroids within the previous 30 days, or those who have received chemotherapy or radiotherapy within the last year). * Presence of active malignancy or any concomitant end-stage organ disease within the last 12 months that, in the investigator's judgment, contraindicates participation in the study. * Hypersensitivity, allergy, or intolerance to any of the components of the study product or standardized study menus (e.g., cow's milk protein allergy \[CMPA\], celiac disease, or non-celiac gluten intolerance). * Current participation or participation in another clinical trial within the previous three months. * Pregnant or breastfeeding women, women seeking pregnancy, or women of childbearing potential who are unwilling to use an effective contraceptive method.
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The study's own enquiry address
This study publishes an address for enquiries. See it below .
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Show contact details
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Genom att skicka in godkänner du våra Användarvillkor
Locations
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Hospital Universitario HM Sanchinarro
RECRUITINGMadrid, Madrid, 28050, Spain
Contact Email: •••••@•••••
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