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New drug combo aims to tame tough eczema

NCT ID NCT07027527

First seen Nov 01, 2025 · Last updated May 21, 2026 · Updated 35 times

Summary

This study tests whether a new combination of two drugs (APG777 and APG990) is safe and how the body processes them in adults with moderate-to-severe atopic dermatitis (eczema). About 86 participants will receive either the new combo or an existing treatment (dupilumab) for 24 weeks, with follow-up lasting over a year. The goal is to see if the new approach can better control the disease, though ongoing management is still needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Investigational Site

    Darlinghurst, New South Wales, 2010, Australia

  • Investigational Site

    Kogarah, New South Wales, 2217, Australia

  • Investigational Site

    Westmead, New South Wales, 2145, Australia

  • Investigational Site

    Woolloongabba, Queensland, 4102, Australia

  • Investigational Site

    Carlton, Victoria, 3053, Australia

  • Investigational Site

    East Melbourne, Victoria, 3002, Australia

  • Investigational Site

    Mitcham, Victoria, 3132, Australia

  • Investigational Site

    Parkville, Victoria, 3050, Australia

  • Investigational Site

    Fremantle, Western Australia, 6160, Australia

  • Investigational Site

    London, Ontario, N6H 5L5, Canada

  • Investigational Site

    Peterborough, Ontario, K9J 5K2, Canada

  • Investigational Site

    Richmond Hill, Ontario, L4B 1A5, Canada

  • Investigational Site

    Toronto, Ontario, M4E 1R7, Canada

  • Investigational Site

    Toronto, Ontario, M4W 2N4, Canada

  • Investigational Site

    Toronto, Ontario, M5A 3R6, Canada

  • Investigational Site

    Montreal, Quebec, H1Y 3L1, Canada

  • Investigational Site

    Québec, Quebec, G1W 1S2, Canada

  • Investigational Site

    Sherbrooke, Quebec, J1G 1X9, Canada

  • Investigational Site

    Hamilton, Waitako, 3204, New Zealand

  • Investigational Site

    Auckland, 1051, New Zealand

Conditions

Explore the condition pages connected to this study.