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New combo attack on hard-to-treat prostate cancer shows promise

NCT ID NCT03503344

First seen Jan 27, 2026 · Last updated Jun 19, 2026 · Updated 26 times

Summary

This study tested whether adding a precise, high-dose radiation treatment (SBRT) to the hormone therapy apalutamide helps control prostate cancer that has stopped responding to standard hormone therapy and spread to a few spots. Twenty-six men with this type of cancer took part. The main goal was to see if the combination could make PSA levels undetectable after 18 months. The approach aims to delay the cancer's progression while keeping side effects manageable.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of California, San Francisco

    San Francisco, California, 94115, United States

Conditions

The condition(s) this trial relates to.

castration-resistant prostate carcinoma metastatic prostate carcinoma prostate adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.