STAGE IV PROSTATE ADENOCARCINOMA AJCC V7

This study is testing whether surgically removing the prostate (cytoreductive radical prostatectomy) combined with standard hormone-blocking drug therapy works better than drug therapy alone for men newly diagnosed with prostate cancer that has already spread. The goal is to see …

This study is testing whether adding a drug called cediranib to another drug called olaparib works better than olaparib alone for men with advanced prostate cancer that has spread and stopped responding to standard hormone therapy. The trial will enroll about 90 men to see which …

This study is for men whose prostate cancer has returned after surgery. It tests if adding a drug called apalutamide to standard radiation therapy works better than radiation alone to keep the cancer from progressing. Apalutamide works by blocking hormones that can fuel prostate …

This study is for men whose prostate cancer has spread and stopped responding to standard hormone therapy and an initial round of chemotherapy. It tests if adding a second chemotherapy drug (cabazitaxel) to a standard hormone-blocking drug (abiraterone) is more effective at contr…

This study is testing different combinations of approved drugs to find better ways to control advanced prostate cancer that has spread and stopped responding to standard hormone therapy. It involves 196 men and uses a personalized approach: after an initial 8-week treatment, pati…